The Acne Blast commercial shows a zitty teen loser who apparently is only a tube of Acne Blast away from dating supermodels. It is notable that this commercial inspires GIR to eat a tube of Acne Blast cream in Rise of the Zitboy.
It isn't clear whether or not the stuff works on humans, but it did fail to cure Zim's pimple which gave rise to the existance of Pustulio.
The star of the commercial is none other than Acne Blast Man, seen at left, an anthropomorphic tube of zit cream who flies to the rescue of those unfortunate enough to be afflicted with blemishes. I find myself wondering if he has a battle cry like the superheroes he resembles...